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They usually decide they're going to stop self-injuring for themselves and instead of leaving self-injury as their main option for negative emotions they move it down the list of things to do or eliminate it altogether. 

They need to be be willing to feel negative and uncomfortable emotions without resorting to self-injury. They often have people to support them through tough times, be it therapists. friends, a significant other, or family. They may go through therapy to learn different ways to cope but not all people do that.

Some people sort of 'grow out of' self-injury naturally. I've seen studies that discuss how by people's thirties a lot of people have stopped self-injuring, some without any major attempt to stop self-injuring. This is not a rule but it's fairly common. There are still self-injurers older than that for those adult self-injurers thinking I'm cutting -- bad word choice -- out of the picture.